C499

C499

A chimpanzee from the Yerkes Regional Primate Research Center at Emory University, which was inoculated with HIV in 1985; in 1995, it developed AIDS, manifested as:
• A decline in CD4+ cells;
• An increase in viral loads in plasma;
• Presence of a virus, HIV-1JC, which is cytopathic for chimpanzee peripheral blood mononuclear cells; and
• The presence of an opportunistic infection and blood dyscrasias.

Other chimps were likely to develop AIDS as well, making them good research models.
References in periodicals archive ?
Comparative experimental results Circuit Depth minDepth minLevelMapIVv3 LUT count LUT count 9sym 5 7 8 C499 4 67 68 C5315 8 500 501 C880 7 130 133 alu2 5 129 130 alu4 5 549 550 apex2 5 150 152 apex4 5 875 881 apex6 4 222 222 apex7 4 67 71 b9 3 37 39 clip 3 44 45 count 3 74 74 des 5 1014 1020 duke2 4 151 152 e64 3 338 339 f51m 3 51 51 rd84 3 13 13 rot 6 204 206 sao2 4 57 57 vg2 3 35 35 4714 4747
Experimental results of PwOptMap mapping tool Estimated Dynamic Power Circuit Depth Optimum Optimal Optimal Depth Depth Depth & Optimal Area 5xp1 3 2,92 2,01 1,56 9symml 5 3,89 2,91 2,65 C499 5 10,76 8,22 7,96 C880 8 16,69 14,67 14,04 alu2 8 14,05 12,89 12,25 apex6 4 22,62 20,58 20,16 apex7 4 10,45 8,92 8,43 count 3 3,52 3,04 2,50 des 5 99,67 96,11 97,44 duke2 4 9,21 8,64 8,93 misex1 2 2,21 2,11 2,19 rd84 4 4,58 4,12 4,47 rot 6 35,51 35,03 34,73 vg2 4 4,32 3,01 3,95 z4ml 3 1,49 1,38 1,32 241,89 223,64 222,58