C1-inactivator

C1-inactivator

one of the six major protease inhibitors of blood; it inhibits clotting factors XIa, XIIa and plasma kallikrein, but not Xa and plasmin.
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However, when added to plasma, hK2 reacts most rapidly with aZ macroglobulin, but it also reacts with C1-inactivator and probably with other inhibitors, which have not yet been positively identified (18).
a2 Macroglobulin and C1-inactivator are plasma inhibitors of human glandular kallikrein.