Corynebacterium diphtheriae

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Cor·y·ne·bac·te·ri·um diph·the·'ri·ae

a bacterial species that causes diphtheria and produces a powerful exotoxin causing degeneration of various tissues, notably myocardium, in humans and experimental animals, and catalyzing the ADP-ribosylation of elongation factor II; virulent strains of this organism are lysogenic; it is commonly found in membranes in the pharynx, larynx, trachea, and nose in cases of diphtheria; it is also found in apparently healthy pharynx and nose in carriers, and occasionally in the conjunctiva and in superficial wounds; it occasionally infects the nasal passages and wounds of horses; it is the type species of the genus Corynebacterium.

Corynebacterium diphtheriae

The causative agent of diphtheria, which produces a potent exotoxin Reservoir Humans Epidemiology Airborne, infected fomites, infected skin; more common in winter, with crowding, hot, dry air Incidence 5/105–US; attack rate in minorities is 5- to 20-fold that of whites Microbiology In culture, C diphtheriae are often arranged in aggregates fancifully likened to Chinese letters

Cor·y·ne·bac·te·ri·um diph·the·ri·ae

(kŏ-rī'nē-bak-tēr'ē-ŭm dif-thēr'ē-ē)
Typespecies of the genus Corynebacterium, thecause of diphtheria. It induces a severe membranous pharyngitis and produces an exotoxin that damages myocardium and other tissues; may also infect superficial wounds; an asymptomatic carrier state is common.
Synonym(s): Löffler bacillus.

Corynebacterium diphtheriae

The causative agent of diphtheria in humans.
See: diphtheria
See also: Corynebacterium