Corynebacterium diphtheriae

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Cor·y·ne·bac·te·ri·um diph·the·'ri·ae

a bacterial species that causes diphtheria and produces a powerful exotoxin causing degeneration of various tissues, notably myocardium, in humans and experimental animals, and catalyzing the ADP-ribosylation of elongation factor II; virulent strains of this organism are lysogenic; it is commonly found in membranes in the pharynx, larynx, trachea, and nose in cases of diphtheria; it is also found in apparently healthy pharynx and nose in carriers, and occasionally in the conjunctiva and in superficial wounds; it occasionally infects the nasal passages and wounds of horses; it is the type species of the genus Corynebacterium.

Corynebacterium diphtheriae

The causative agent of diphtheria, which produces a potent exotoxin Reservoir Humans Epidemiology Airborne, infected fomites, infected skin; more common in winter, with crowding, hot, dry air Incidence 5/105–US; attack rate in minorities is 5- to 20-fold that of whites Microbiology In culture, C diphtheriae are often arranged in aggregates fancifully likened to Chinese letters

Cor·y·ne·bac·te·ri·um diph·the·ri·ae

(kŏ-rī'nē-bak-tēr'ē-ŭm dif-thēr'ē-ē)
Typespecies of the genus Corynebacterium, thecause of diphtheria. It induces a severe membranous pharyngitis and produces an exotoxin that damages myocardium and other tissues; may also infect superficial wounds; an asymptomatic carrier state is common.
Synonym(s): Löffler bacillus.

Corynebacterium diphtheriae

The causative agent of diphtheria in humans.
See: diphtheria
See also: Corynebacterium
References in periodicals archive ?
A study in Poland showed a discriminatory capacity of some of the VNTR loci in C.
Toxigenicity testing is considered an important criterion for notifying C.
The other possible reason suspected by Singh et al (10) was misdiagnosis and poor handling of the specimen in the peripheral areas which certainly affect the isolation of C.
Taking these data and the literature review into consideration, C.
Homelessness, alcohol abuse, IVDU, and diabetes mellitus were mentioned in the literature as risk factors for C.
During 2000-2009, a total of 32 deaths caused by diphtheria were reported in Latvia, and 13 deaths (10 caused by C.
paragraph]) Includes 2 case-patients infected with C.
All feline isolates produced 7-15 meq/L of propionic acid among fermentation products, a feature associated with C.
Medical personnel should include this in civilian as well as military health services, since our cases indicate that toxigenic C.
In the United Kingdom, 17 patients with cases of cutaneous diphtheria due to toxigenic C.