C-reactive proteins

A group of proteins that increase rapidly in amount in the blood during infections. They promote the binding of COMPLEMENT, a process known as opsonization (From Latin, opsonare , to lay in provisions for the table). Human C-reactive protein consists of five identical POLYPEPTIDE units arranged in a cyclical pattern. The protein has the power of binding to micro-organisms that have phorphorylcholine in their cell membranes. The complex then activates complement and in this way encourage the destruction and removal of invaders by phagocyte cells (PHAGOCYTOSIS).

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Blood samples were drawn from every neonate for culture sensitivity and measurement of serum C-reactive proteins.

Objective: To evaluate the adequacy of serum C-reactive protein (CRP) in diagnosing neonatal sepsis and role of CRP in determining the duration of antibiotic treatment in neonatal sepsis.

Metabolic and scintigraphic studies of radioiodinated human C-reactive protein in health and disease.

Validation of serum C-reactive protein for the diagnosis and monitoring of antibiotic therapy in neonatal sepsis

To avoid unnecessary removal of normal appendix more laboratory tests like C-Reactive Proteins (CRP) have been evolved.

Many studies have been published on quantitative analysis of C-reactive protein which is an acute phase reactant protein that is produced in the liver.

C-reactive protein is basically an acute phase reactant, which has been shown persistently elevated in cases of acute appendicitis.

A comprehensive study on diagnostic value of quantitative C-reactive protein measurement in acute appendicitis

Case records of all newborns presenting with signs and symptoms of septicemia with/without pneumonia and/or meningitis were further analysed for blood culture, interleukin -6 levels and C-reactive proteins results which were compared.

C-reactive proteins reacted late and their maximum concentrations appeared at 24 hours.

e within 1-4 hours of a sepsis stimulus15 -16 while, C-reactive proteins peak after 24 hours of the septic stimulus.

Early detection of bacterial sepsis in newborns

The Celltac Chemi, which is based on the latex agglutination turbidmetric immunoassay, can rapidly measure C-reactive proteins (CRPs) in the blood.

Nihon Kohden Launches Two New Compact Analyzers in Celltac Series

Braunwald in his scholarly lecture has listed some emerging cardiovascular risk factors, C-reactive proteins being one of them.

3) The biomolecule with the greater body of research both from a molecular and epidemiological perspective is C-Reactive Protein (CRP), a plasma protein of the pentraxin family and an acute phase reactant, which displays high sensitivity as a general inflammation marker.

Correlation between serum hs-CRP and LDL cholesterol as a predictor of cardiovascular diseases

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