Transduction pathways involved in the up-regulation of c-fos
Mollugin inhibits RANKL-induced osteoclast differentiation by suppressing c-Fos
and NFATc1 activity
These sections were then incubated for 2- 3 days in primary antibody of oncogene rabbit c-Fos
at the dilution of 1:3000 plus normal goat serum, Triton X-100 and.
Earlier patents covering oncology target protein kinase Akt, transcription factor Hif-1 and oncogene product c-fos
Nc-5-s decreased LPS-induced phosphorylation of the extracellular regulated kinase (ERK) 1/2 and Akt kinase, but did not affect phosphorylation of the p38 kinase, activation of the nuclear factor kappa B pathway, nor DNA binding of c-fos
AP1 comprises c-FOS
and c-JUN, and these genes were assessed relative to glyceraldehyde 3-phosphate dehydrogenase (GAPDH) using qRT-PCR; primer sequences are shown in Supplemental Material, Table S2 (http://dx.
To gauge whether or not the naked mole-rats were responding physiologically to the acidic environment, the scientists measured a protein called c-Fos
, which can help determine if nerve cells are firing.
Downstream targets of CD95 essential for cell growth, such as JNK, c-Fos
and Egr1, also decreased their activity when the 'death receptor' was blocked.
Therefore, we studied the involvement of iron and ROS in the modulation of Jun N-terminal kinase 2 (JNK2) activity, c-jun and c-fos
mRNA levels, key signaling steps in the transcriptional control of matrix-degrading metalloprotease (MMP)-1/interstitial collagenase and MMP-3/stromelysin-1 after UVB irradiation of human dermal fibroblasts in vitro.
Presentation Title: Effects of a topical alprostadil cream on expression of c-fos
and oxytocin like immunoreactivity in hypothalamus of female rats.
In a second study, Repligen investigators injected secretin into mice and over the next 6 hours looked in the brain for signs of a protein called c-fos
Patent 7,388,014 covers Rexahn's anticancer candidate, RX-0183 and related compounds, and are targeted, small molecule quinazoline analogues that inhibit key molecules such as c-Fos
and Akt proteins.