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Bystander Effect

   Also found in: Wikipedia 0.01 sec.
Bystander Effect
Immunology See Bystander suppression
Molecular biology The secondary effects on adjacent cells and tissues triggered by treatment of a primary target with a therapeutic agent.
Molecular medicine An anticancer effect of unknown origin evoked by some forms of gene therapy in which a treatment—e.g., p53 therapy—kills more tumour cells than can be accounted for by the number of cells actually expressing an inserted gene bystander effect
Psychology Bystander apathy A type of social phenomenon in which person ‘A' is less likely to assist a person 'B' in need of help, when other people are present, than when ‘A’ is alone


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Chapters focusing on cancer models cover oncogenetic trees, stochastic multi-state models of carcinogenesis, models of cancer metastasis, cell cycle regulation by radiation, genomic instability, DNA damage and repair, bystander effects of radiation, epigenetic hypotheses, multiple pathways of colon cancer, and the most recent discoveries in cancer biology and how they are transformed into stochastic models of carcinogenesis.
This finding is probably explained by an uncontrolled covariate, bystander effect (Hudson & Bruckman, 2004).
In the early 1990s, two previously unacknowledged effects of radiation were reported, genomic instability and the bystander effect (Appendix).
 
 
 
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