phenylbutazone

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phenylbutazone

 [fen″il-bu´tah-zōn]
a nonsteroidal antiinflammatory drug administered orally in the short-term treatment of severe rheumatoid disorders unresponsive to less toxic agents. It is given for periods of less than one week because it can cause aplastic anemia and agranulocytosis.

phenylbutazone

/phen·yl·bu·ta·zone/ (-bu´tah-zōn) a nonsteroidal antiinflammatory drug used in the short-term treatment of severe rheumatoid disorders unresponsive to less toxic agents.

phenylbutazone

Therapeutics An NSAID tightly bound to plasma proteins. See NSAIDs.

phenylbutazone

A non-steroidal anti-inflammatory drug (NSAID) once widely used but now available for use in hospitals only because of its tendency to cause HEART FAILURE from fluid retention and severe blood disorders. It is used, under specialist supervision, in cases of ANKYLOSING SPONDYLITIS.

phenylbutazone

a powerful anti-inflammatory drug first used in the 1940s in the treatment of arthritis. Limited by its potentially serious side effects (including fatalities), it is now rarely used in humans (ankylosing spondylitis is an exception) but interestingly is used in equestrian sports to treat soft tissue injuries in horses.

phenylbutazone

pyrazole painkiller, used to treat ankylosing spondylitis

phenylbutazone

a nonsteroidal anti-inflammatory drug resembling cortisone in its action; used in the treatment of painful conditions of joints and skeletal muscles. It has powerful analgesic and antipyretic effects, but causes bone marrow suppression with high doses or prolonged administration.