Burkholderia cepacia

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Burkholderia cepacia

a bacterial species found in rotted onions and in clinical specimens; commonly found in respiratory secretions in patients with cystic fibrosis, it is frequently resistant to many antibiotics.
Synonym(s): Pseudomonas cepacia

Burkholderia cepacia

formerly Pseudomonas cepacia. A group of bacteria found in the environment that are often resistant to common antibiotics. Immunocompromised persons or those with chronic lung disease, especially cystic fibrosis, are susceptible to infection. In patients without cystic fibrosis, B. cepacia infections are almost all nosocomial or related to IV drug abuse. Outbreaks have been related to intra-aortic balloon pumps, contaminated water sources, respiratory therapy equipment such as reusable electronic ventilator probes or contaminated disinfectants. A variety of approaches including strict segregation of cystic fibrosis patients based on the presence of this organism have been tried in order to reduce nosocomial transmission. Even a single significant nosocomial infection with B. cepacia may warrant investigation.

Burkholderia cepacia

A group of at least 17 Pseudomonas-like gram-negative bacteria found in the environment—e.g., plants, water, soil and in hospital—which may colonise the respiratory tract.

Clinical findings
May cause life-threatening pneumonia in patients with cystic fibrosis, chronic granulomatous disease and lung transplants; B cepacia may also cause urinary tract infections and infect sterile body sites.
 
Epidemiology
Transmitted by direct physical contact from contaminated environmental sources, fluids and medical devices, by aerosol or person-to-person.

Burkholderia cepacia

Pseudomonas cepacia Bacteriology A bacterium found in the environment–eg, plants, water, soil, and in hospital environment, which may colonize the respiratory tract of Pts with cystic fibrosis; transmitted by direct physical contact from contaminated environmental sources, fluids and medical devices and, by aerosol, person-to-person Clinical May cause life-threatening URIs in Pts with cystic fibrosis, chronic granulomatous disease; also associated with UTIs and may infect sterile body sites

Burk·hol·der·i·a ce·pa·ci·a

(bŭrk-hol-der'ē-ă sē-pā'shē-ă)
A bacterial species found in rotted onions and in clinical specimens; commonly found in respiratory secretions in patients with cystic fibrosis, it is frequently resistant to many antibiotics. Formerly known as Pseudomonas cepacia.
References in periodicals archive ?
Matrix-assisted laser desorption ionisation-time-of-flight mass spectrometry of intact cells allows rapid identification of Burkholderia cepacia complex.
Burkholderia cepacia complex (BCC) can be particularly devastating, highly virulent, cystic fibrosis (CF) pathogens that are also able to cause nosocomial infections among other groups of debilitated patients (1).
The multifarious, multireplicon Burkholderia cepacia complex.
Burkholder showed that the cause was a bacterium that now bears his name, one of the nine closely related lineages within what's called the Burkholderia cepacia complex (BCC).
This collection of 13 articles brings together the most recent research and applications, covering such topics as the need for diversity and the role of Burkholderia; epidemiology, typing, comparative genetics and population genetics of Burkholderia species; antibiotic resistance of Burkholderia species; polysaccharides; interactions of species with the phagocytic system; beneficial interactions with plants; the phytopathogenic Burkholderia; biodegration of pollutants by Burkholderia; molecular mechanisms of virulence of Burkholderia pseudomallei and Burkholderia mallei; model systems of Burkholderia cepacia complex infection; social behaviors of members of the genus Burkholderia; and intercellular survival of Burkholderia cepacia complex isolates.
He had Staphylococcus aureus liver abscesses at ages 5 and 10 years, Burkholderia cepacia complex pneumonia at age 6 years, and Serratia marcescens pneumonia at age 12 years.
Members of the Burkholderia cepacia complex (Bcc), found in many environments, are associated with clinical infections.
We report the first case of community-acquired bacteremia with Burkholderia fungorum, a newly described member of the Burkholderia cepacia complex.
Typical pathogens in respiratory secretions of patients with CF include Pseudomonas aeruginosa, Staphylococcus aureus, Haemophilus influenzae, and Burkholderia cepacia complex (1-3).
To date, the genus Burkholderia comprises more than 30 species, including the Burkholderia cepacia complex, B.
Development of rRNA-based PCR assays for identification of Burkholderia cepacia complex isolates recovered from cystic fibrosis patients.
In the article "Epidemiology of Burkholderia cepacia Complex in Patients with Cystic Fibrosis, Canada" by David P.