Burkholderia cepacia


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Burkholderia cepacia

a bacterial species found in rotted onions and in clinical specimens; commonly found in respiratory secretions in patients with cystic fibrosis, it is frequently resistant to many antibiotics.
Synonym(s): Pseudomonas cepacia

Burkholderia cepacia

formerly Pseudomonas cepacia. A group of bacteria found in the environment that are often resistant to common antibiotics. Immunocompromised persons or those with chronic lung disease, especially cystic fibrosis, are susceptible to infection. In patients without cystic fibrosis, B. cepacia infections are almost all nosocomial or related to IV drug abuse. Outbreaks have been related to intra-aortic balloon pumps, contaminated water sources, respiratory therapy equipment such as reusable electronic ventilator probes or contaminated disinfectants. A variety of approaches including strict segregation of cystic fibrosis patients based on the presence of this organism have been tried in order to reduce nosocomial transmission. Even a single significant nosocomial infection with B. cepacia may warrant investigation.

Burkholderia cepacia

A group of at least 17 Pseudomonas-like gram-negative bacteria found in the environment—e.g., plants, water, soil and in hospital—which may colonise the respiratory tract.

Clinical findings
May cause life-threatening pneumonia in patients with cystic fibrosis, chronic granulomatous disease and lung transplants; B cepacia may also cause urinary tract infections and infect sterile body sites.
 
Epidemiology
Transmitted by direct physical contact from contaminated environmental sources, fluids and medical devices, by aerosol or person-to-person.

Burkholderia cepacia

Pseudomonas cepacia Bacteriology A bacterium found in the environment–eg, plants, water, soil, and in hospital environment, which may colonize the respiratory tract of Pts with cystic fibrosis; transmitted by direct physical contact from contaminated environmental sources, fluids and medical devices and, by aerosol, person-to-person Clinical May cause life-threatening URIs in Pts with cystic fibrosis, chronic granulomatous disease; also associated with UTIs and may infect sterile body sites

Burk·hol·der·i·a ce·pa·ci·a

(bŭrk-hol-der'ē-ă sē-pā'shē-ă)
A bacterial species found in rotted onions and in clinical specimens; commonly found in respiratory secretions in patients with cystic fibrosis, it is frequently resistant to many antibiotics. Formerly known as Pseudomonas cepacia.
References in periodicals archive ?
Safety and efficacy have not been demonstrated in patients under the age of 6 years, patients with FEV1 <25% or >75% predicted, or patients colonized with Burkholderia cepacia.
Misidentification of Burkholderia pseudomallei as Burkholderia cepacia by the Vitek 2 system.
In October 2014, Nutek issued a nationwide voluntary product recall at the retail level of all lots of baby wipes manufactured under the brand names Cuties, Diapers, com, Femtex, Fred's, Kidgets, Member's Mark, Simply Right, Sunny Smiles, Tender Touch, and Well Beginnings, because some packages might have contained a bacteria called Burkholderia cepacia (B.
In October 2014, Nutek issued a nationwide voluntary product recall at the retail level of all lots of baby wipes manufactured under the brand names Cuties, Diapers, com, Femtex, Fred's, Budgets, Member's Mark, Simply Right, Sunny Smiles, Tender Touch, and Well Beginnings, because some packages might have contained a bacteria called Burkholderia cepacia (B.
But because the 18-year-old has a bug in his lungs, known as burkholderia cepacia, he is not eligible for a transplant.
In a patient with cystic fibrosis infected with multidrug-resistant Burkholderia cepacia, who was treated with meropenem 2 g 8-hourly as a 3-hour infusion, concentrations >8 [micro]g/mL were achieved for 52% of the dosing interval, with subsequent improvement.
Ayrica Staphylococcus aureus, Aeromonas hydrophilia, Enterobacter turleri, Proteus turleri, Burkholderia cepacia, Serratia marcescens, Aspergillus turleri, Mucor turleri, Escherichia coli ve Candida turleri ile de klinik olarak benzer lezyonlarin gelisebildigi saptanmistir (7).
In a classic whodunnit--or rather what dunnit--the infection control team (ICT) at Waikato District Health Board (DHB) eventually solved the mystery surrounding a Burkholderia cepacia (B cepacia) outbreak in the neonatal intensive care unit (NICU) last year.
The most prevalent species observed was Candida kruseii (19 banknotes, 27%) followed by Burkholderia cepacia (nine banknotes, 13%).
Burkholderia cepacia complex (BCC) can be particularly devastating, highly virulent, cystic fibrosis (CF) pathogens that are also able to cause nosocomial infections among other groups of debilitated patients (1).
Ultrasound procedures and transmission gel have been implicated in the spread of several bacterial pathogens including Burkholderia cepacia.