buffalopox


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buffalopox

a disease caused by a virus which is antigenically identical to cowpox virus; it is clinically the same as cowpox.
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Buffalopox (BPX) is a zoonotic infection affecting humans, cattle and buffalo.
Key word: buffalopox, hematology, gross pathology, inclusion bodies.
Buffalopox, camelpox, and elephantpox produce a localized nodular lesion that is self-limiting.
Vaccination for cowpox, feline cowpox, buffalopox, and horsepox is not practiced.
During the past few decades, reports about emerging and reemerging zoonotic VACV and buffalopox virus have increased, as have the number of severe cases of disease caused by the viruses (2,3).
To the Editor: In India, buffalopox virus (BPXV), a variant of vaccinia virus, is associated with severe disease outbreaks among buffaloes (1,2), cattle (3), and humans in contact with these animals (1,4).
Sequence analysis of C18L gene of buffalopox virus: PCR strategy for specific detection and differentiation of buffalopox from orthopoxviruses.
Another VACV subspecies, buffalopox virus (BPXV), has been isolated from buffaloes (Bubalus bubalis) in rural areas in India and causes clinical signs that resemble those seen during BV outbreaks in Brazil (6).
In India, some strains of buffalopox, transmitted to humans through buffaloes, appear to be vaccinia.
We compared molecular sequence data from 3 genes and a variable region of the poxvirus genome (Table 1) among BRZ-VACV isolates, available vaccine strains related to those used during the eradication campaign in Brazil, and other VACVs isolated from domestic animals (including endemic buffalopox virus in India [15-17] and horsepox virus [HSPV] from Asia [18]).
The VACV variants buffalopox and rabbitpox have originated from VACV subspeciation (13).
These facts indicate the long-term establishment and active circulation of different vaccinialike viruses in the wild in South America, similar to the well-documented establishment of buffalopox virus in India (19,20).