The prevalence and significance of Brunn's nests
, cystitis cystica and squamous metaplasia in normal bladders.
This variant of urothelial bladder cancer often resembles clinical and histological features of inverted papilloma, von Brunn's nests
(VBNs), cystitis cystica, nephrogenic metaplasia and sometimes usual TCC.
1] Cystitis cystica occurs when von Brunn's nests
grow into the lamina propria forming cysts, while cystitis glandularis describes the metaplastic change into goblet cells.