BOOP

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BOOP

BOOP

Bronchiolitis obliterans organising pneumonia. A disease once considered a form of interstitial pneumonia.

Aetiology
Prior infectious bronchiolitis; toxic inhalants; as part of various disease processes, including hypersensitivity pneumonitis (extrinsic allergic alveolitis), collagen vascular disease and drug hypersensitivity; the nonspecific nature of the BOOP reaction makes this diagnosis difficult.

Clinical findings
Cough, dyspnoea, “flu” symptoms; 50% recover, 12% eventually die of disease, many develop usual interstitial pneumonia; obstructive symptoms are limited to smokers, most of whom have restrictive disease and impaired diffusing capacity; remission may follow corticosteroid therapy.

DiffDx
Organisation in infections, pneumonias associated with other conditions—e.g., COPD, cystic fibrosis, bronchiectasis, distal obstruction, aspiration diffuse alveolar damage, eosinophilic pneumonia, collagen vascular disease—allergic reactions (e.g., extrinsic allergic alveolitis, vasculitis) and reactive to other processes (abscesses, infarcts, tumours).
 
Imaging
Patchy ground-glass appearance on AP chest film.

BOOP

Bronchiolitis obliterans organizing pneumonia A disease once considered a form of interstitial pneumonia Etiology Obscure; ? associated with toxic fumes, infection, connective tissue disease Clinical Cough, dyspnea, 'flu' symptoms, 50% recovery, 12% BOOPs eventually die of disease, many develop usual interstitial pneumonia; obstructive symptoms are limited to smokers, most of whom have restrictive disease and impaired diffusing capacity, remission may follow use of corticosteroids Radiology Patchy ground-glass appearance on AP chest film DiffDx Organization in infections, pneumonias associated with other conditions–eg COPD, cystic fibrosis, bronchiectasis, distal obstruction, aspiration diffuse alveolar damage, eosinophilic pneumonia, collagen vascular disease, allergic reactions–eg extrinsic allergic alveolitis, vasculitis, and reactive to other processes–abscesses, infarcts, tumors

BOOP

Abbreviation for bronchiolitis obliterans with organizing pneumonia.
References in periodicals archive ?
Bronchiolitis obliterans organizing pneumonia as the first manifestation of polymyositis.
Bronchiolitis obliterans organizing pneumonia in polymyositis: a case report with longterm survival.
Drug-induced bronchiolitis obliterans organizing pneumonia.
Bronchiolitis obliterans organizing pneumonia following chlorambucil treatment for chronic lymphocytic leukemia.
Bronchiolitis obliterans organizing pneumonia after orthotopic liver transplantation.
Bronchiolitis obliterans organizing pneumonia in a patient with non-Hodgkin's lymphoma following R-CHOP and pegylated filgrastim.
Bronchiolitis obliterans organizing pneumonia (BOOP) after thoracic radiotherapy for breast carcinoma.
Bronchiolitis obliterans organizing pneumonia (BOOP) in a child with mild-to-moderate asthma: evidence of mast cell and eosinophil recruitmentin lung specimens.
Pathologic aspects of bronchiolitis obliterans organizing pneumonia.