Brodmann areas

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Brod·mann ar·e·as

areas of the cerebral cortex mapped on the basis of cytoarchitectural patterns. See: cerebral cortex.

The German physician Korbinian Brodmann (1868-1918) was diverted from plans to enter general practice by a long convalescence during which he worked at a sanatorium for nervous diseases. After advanced studies in neurology, neuroanatomy, pathology, and psychiatry, he began an investigation of the comparative anatomy of the mammalian cortex at the Neurobiological Laboratory of the University of Berlin. Earlier workers had divided the cortex into six principal layers on the basis of their proportions of pyramidal, stellate, and fusiform cells. Using the newly developed staining technique of Nissl, Brodmann distinguished about 50 zones of the cortex on the basis of subtle differences in cell type, size, density, and lamination, and correlated his anatomic findings with studies on localization of function in humans, subhuman primates, and other mammals. His cortical map and numbering system, published in 1909, became standard methods for distinguishing areas of cortex, and are still widely used by clinical neurologists and neurosurgeons. Although later workers have published revisions of his work, subdivided his areas, and substituted letters for his numbers, modern experimental methods have largely vindicated his cortical localizations, both anatomic and functional. see also figure at cerebral cortex.

Brod·mann ar·e·as

(brōd'mahn ar'ē-ăz)
Regions of the cerebral cortex distinguished on the basis of histologic differences and presumed differences in function.

Brodmann areas

(brōd′man″)
[Korbinian Brodmann, Ger. neurologist, 1868–1918]
The division of the cerebral cortex into 47 areas. This was originally done on the basis of cytoarchitectural characteristics, but the areas are now classified according to their functions.

Brodmann,

Korbinian, German neurologist, 1868-1918.
Brodmann area 41 - Synonym(s): primary auditory cortex
Brodmann area 44 - Synonym(s): Broca center
Brodmann areas - areas of cerebral cortex mapped out on the basis of cortical cytoarchitectural patterns.
References in periodicals archive ?
However, there are some difference in Brodmann areas 4, 6, 8, Brodmann areas 7, 39, 40, Brodmann areas 18, 19, 22 and Brodmann areas 13, 24, 32, 28.
Jude Medical owns the intellectual property rights and has various patents pending for the use of neurostimulation at Brodmann Area 25.
The results of the study showed that DBS therapy targeted to an area of the brain known as Brodmann Area 25 provided noticeable improvement in depression symptoms and increased overall quality of life in patients who typically don't respond to treatment.
The BROADEN study is investigating whether or not stimulating an area of the brain known as Brodmann Area 25 (BA25) with a deep brain stimulation (DBS) system is a safe and effective method for treating severe depression.
This study profiles 21 patients with DBS therapy in the area of the brain known as Brodmann Area 25, most of whom have completed one year of post-surgery evaluation.
This study is researching a specific area in the brain called Brodmann Area 25 that is thought to be involved in depression.
NYSE:STJ) today announced pilot study results from the first multi-center study investigating deep brain stimulation (DBS) of Brodmann Area 25 for major depressive disorder.
Brodmann Area 25 Study Moves Forward With Enrollment of First Patient
Research to focus on the Brodmann Area 25 region of the brain
In contrast, the rostral/ventral "affective area (corresponding to Brodmann areas 24a, 24b, 24c, 25, 32, 33) is linked to the limbic system and orbitofrontal regions.
Semi-quantitative analysis of perfusion of Brodmann areas in the differential diagnosis of cognitive impairment in Alzheimer's disease, fronto-temporal dementia and mild cognitive impairment.
Fisher (1998) discusses the dorsolateral prefrontal circuit which she believes originates in Brodmann areas 9 and 10 commencing on the lateral surface of the anterior frontal lobe.