British Foetal Haemoglobin

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A congenital hemoglobinopathy due to a regulatory defect in postnatal gamma chain synthesis; 20% of the Hb in homozygotes and 3.5–10% in heterozygotes is HbF; it is of clinical importance as it may mimic massive feto-maternal haemorrhage and thereby possible overdosage of Rh immune globulin

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