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Brill-Zinsser disease[bril´ zin´ser]
Brill-Zins·ser dis·ease(bril zinz'sĕr),
an endogenous reinfection associated with the "carrier state" in patients who previously had epidemic typhus fever; it is a rather mild disease and may be mistaken for endemic (murine) typhus; first described by Brill in New York City but not recognized as a recrudescent form of epidemic typhus until after the work of Zinsser.
Etymology: Nathan E. Brill, American physician, 1860-1925; Hans Zinsser, American bacteriologist, 1878-1940
a mild form of epidemic typhus that recurs in a person who appears to have completely recovered from a severe case of the disease years earlier. Some rickettsiae remain in the body after the symptoms of the disease abate, causing the recurrence of symptoms, especially when stress, illness, or malnutrition weakens the person. Treatment with antibiotics may eradicate the organism. See also epidemic typhus, murine typhus, rickettsiosis, typhus.
Brill-Zinsser diseaseA relapse of epidemic typhus caused by dormant Rickettsia prowazekii, which is reactivated due to intercurrent disease.
Brill-Zins·ser dis·ease(bril-zin'sĕr di-zēz')
Brill,Nathan Edwin, U.S. physician, 1860-1925.
Brill disease - Synonym(s): Brill-Zinsser disease
Brill-Symmers disease - obsolete term for nodular lymphoma.
Brill-Zinsser disease - an endogenous reinfection associated with the "carrier state" in persons who previously had epidemic typhus fever. Synonym(s): Brill disease; recrudescent typhus fever; recrudescent typhus
Zinsser,Hans, U.S. bacteriologist and immunologist, 1878-1940.
Brill-Zinsser disease - see under Brill