Breslow's thickness

Breslow's thickness

system of measurement predictive of melanoma prognosis; i.e. <0.75 mm thick = good prognosis, >0.75 mm thick = less favourable prognosis (see Table 1)
Table 1: Clarke's levels, denoting the level of invasion of a skin tumour
LevelFeature
ILesion confined to epidermis (i.e. in situ)
IIEpidermal lesion has just invaded into upper dermis
IIIEpidermal lesion has significantly invaded upper dermis
IVEpidermal lesion has invaded as far as deeper reticular dermis
VEpidermal lesion has invaded through dermis into subcuticular tissues

The greater the depth of lesion penetration, the more liable it is to undergo metastasis.