Breslow thickness

(redirected from Breslow's depth)
Also found in: Wikipedia.

Bres·low thick·ness

(bres'lō),
maximal thickness of a primary cutaneous melanoma measured in tissue sections from the top of the epidermal granular layer, or from the ulcer base (if the tumor is ulcerated), to the bottom of the tumor; metastatic rates correlate closely with tumor thickness.

Breslow thickness

The greatest thickness of a primary cutaneous melanoma, measured in millimeters in a biopsy specimen from the granular layer of the epidermis down to the deepest point of invasion. Thickness is part of the TNM staging of melanoma and is also used as a prognostic factor. In general, the thicker the lesion the worse the prognosis. See cancer staging.

Bres·low thick·ness

(brez'lō thik'nĕs)
Maximal thickness of a primary cutaneous melanoma measured in tissue sections from the top of the epidermal granular layer, or from the ulcer base (if the tumor is ulcerated), to the bottom of the tumor; metastatic rates correlate closely with tumor thickness.

Breslow,

Alexander, U.S. pathologist, 1928-1980.
Breslow thickness - maximal thickness of a primary cutaneous melanoma.
References in periodicals archive ?
Using the t test for continuous variables or [chi square] test for categorical variables, we found that the median Breslow's depth was 2.
found that the Breslow's depth, younger age, angiolymphatic invasion, mitotic rate and trunk or lower extremity location were predictive of a positive SLN biopsy result [1, 16].
In this study, the results of comparing the data of SLN+ and SLN- patients within the study group showed that median Breslow's depth was 4.
Breslow's depth of invasion (measured in hundredths of a millimeter) and Clark's level of invasion into the layers of the dermis (papillary dermis, reticular dermis, and subcutaneous layer) are both important components of the diagnosis, as they guide therapy and yield prognostic information.