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breakthrough bleeding |
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breakthrough bleeding, the escape of uterine blood between menstrual periods, a possible side effect of fibroids or oral contraceptive use. breakthrough bleeding Gynecology A term applied to various gynecologic “bleeds,” usually refers to mid-cycle bleeding in OC users, and is attributed to insufficient estrogens; the term is not applied to abnormal bleeding in
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Interestingly, Searle's compound benefitted from an accidental contamination of norethynodrel with a tiny amount of estrogen (mestranaol), a combination which reduced breakthrough bleeding during the cycle of treatment. Nausea, vomiting, and breakthrough bleeding are common side effects that may subside within the first three months of use. |
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