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Breakage Syndrome

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Breakage Syndrome
Any molecular disease characterised by chromosomal breaks and rearrangements that increase risk of CA—e.g., Bloom and Fanconi syndromes, ataxia-telangiectasia, xeroderma pigmentosum


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This not only improves the chances of extending your youthfulness but also would prove beneficial in curbing the possibility of the occurrence of aging related syndromes like Werner syndrome, Alaxia telangiectasia, Bloom syndrome, Fanconi anemia, Nijmegen breakage syndrome and so on.
Coverage includes the clinical features of AT, mutations in the AT mutated gene, cell signaling in AT, DNA damage and repair in AT, protein-protein interactions in AT, chromosomal instability in AT, cell cycle defects and apoptosis in AT, oxidative stress and AT, oncogenesis in AT, AT and its overlap with Nijmegen Breakage Syndrome and ataxia-like disorders, and animal models for AT.
1992; Yunis 1983)--by numerous clinical observations, in particular, of patients suffering from hereditary chromosome breakage syndromes (Mathur et al.
 
 
 
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