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BRCA2
(redirected from Brca2 protein)

    Also found in: Wikipedia 0.01 sec.
BRCA2 (bär-s-t)
n.
A tumor suppressor gene that, when inherited in a mutated state, is associated with the development of various cancers, especially breast and ovarian cancer.
BRCA2,
symbol for a breast cancer gene with activity similar to that of BRCA1.
BRCA2
Molecular oncology A tumor suppressor gene linked to breast and ovarian CA See Tumor suppressor gene.
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The BRCA1 and BRCA2 protein products are classified as tumour suppressor genes and are involved in DNA repair, genomic stability, transcriptional regulation and cell cycle control.
Breast cancer is the most common cancer in South African women by Loubser, Frieda; Edge, Jenny; Fieggen, Karen / CME: Your SA Journal of CPD
The understanding of the functional role of BRCA1 and BRCA2 proteins has led to the development of trials of poly(ADP-ribose) polymerase (PARP) inhibitors and platinum- versus taxane-based chemotherapy in patients with BRCA1/2-related metastatic breast cancer [3].
Recent advances in the genetics of susceptibility to and treatment of ... by Newman, William G.; Evans, D. Gareth / Advances in Breast Cancer
 
 
 
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