FABP7

(redirected from Brain-type fatty acid-binding protein)

FABP7

A gene on chromosome 6q22-q23 that encodes a brain fatty acid-binding protein possibly involved in the transport of an as-yet unknown hydrophobic ligand with potential morphogenic activity during CNS development. FABP7 is required for establishing the radial glial fibre system in the developing brain, which is necessary for the migration of immature neurons to establish cortical layers.
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7] Nonstandard abbreviations: A-, H-, L-, E-, I-, and B-FABP, adipocyte, heart-type, liver-type, keratinocyte, intestine-type, and brain-type fatty acid-binding protein, respectively; apo E, apolipoprotein E; 2-DE, 2-dimensional gel electrophoresis; MS/MS, tandem mass spectrometry; SDS-PAGE, sodium dodecyl sulfate-polyacrylamide gel electrophoresis; BMI, body mass index; and HOMA, homeostasis model assessment.