cerebral ischemia

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Related to Brain ischemia: Cerebral ischemia

cerebral ischemia,

n the reduction or loss of oxygen to the cerebrum; prolonged ischemia may lead to cerebral infarction.


deficiency of blood in a part, due to functional constriction or actual obstruction of a blood vessel.

cerebral ischemia
brain anoxia.
myocardial ischemia
deficiency of blood supply to the heart muscle, due to obstruction or constriction of the coronary arteries.
renal ischemia
severe or prolonged ischemia causes irreversible renal failure and death from uremia. Called also ischemic nephrosis.
References in periodicals archive ?
Coverage of the Brain Ischemia pipeline on the basis of route of administration and molecule type.
Brain ischemia and reperfusion: molecular mechanisms of neuronal injury.
Siesjo BK, Bengtsson F: Calcium fluxes, calcium antagonist, and calcium-related pathology in brain ischemia, hypoglycemia, and spreading depression: A unifying hypothesis.
In addition, in a rat middle cerebral artery occlusion reperfusion brain ischemia model, IV bolus of CV1013 followed by infusion after occlusion resulted in a 50% reduction of mean brain infarct volume.
XERECEPT(R) works to reduce edema, defined as an abnormal increase in brain water content, which can have dire consequences, potentially leading to brain ischemia (stroke), herniation, and death.
chairman and chief executive officer, further commented: "We are currently conducting three Phase II trials on CPC-111 and two Phase II trials on CPC-211 (our brain ischemia drug).
DIH may lower the cerebral capillary permeability, cerebral index, and cerebral water content in rats with cerebral ischemia, thus attenuating brain edema induced by brain ischemia (Zhang et al.
Gress is recognized nationally for his expertise in neurocritical care and stroke, with particular clinical research interests in acute brain ischemia -- a condition in which a constricted or obstructed blood vessel reduces blood flow in the brain, causing a dangerous lack of oxygen.
Ginaton, extracted from ginkgo biloba leaves, has been used as a therapeutic agent in lung and brain ischemia (Reynolds and Hastings, 1995; Aoshima et al.
Cluster Analysis of Gene Expression After Brain Ischemia Reveals Multiple Expression Patterns Associated with Specific Cellular Processes, Poster Presentation in location WW12; M.
During brain ischemia, excessive amounts of glutamate are released from vesicles in pre-synaptic neurons, overstimulating glutamate receptors in post-synaptic neurons, especially N-methyl-D-aspartate receptors (White et al.
The scope of work under the grant also includes examination of these compounds in an animal model of transient focal brain ischemia to evaluate in vivo efficacy and toxicity.

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