Bowen disease


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Bow·en dis·ease

(bō'wĕn),
a form of intraepidermal carcinoma characterized by the development of slowly enlarging pinkish or brownish papules or eroded plaques covered with a thickened horny layer; microscopically, there is dyskeratosis with large round epidermal cells with large nuclei and pale-staining cytoplasm which are scattered through all levels of the epidermis.

Bow·en dis·ease

(bō'ĕn di-zēz')
A form of intraepidermal carcinoma characterized by the development of slowly enlarging pinkish or brownish papules or eroded plaques covered with a thickened horny layer; microscopically, there is dyskeratosis with large round epidermal cells with large nuclei and pale-staining cytoplasm that are scattered through all levels of the epidermis. Primary treatment includes curettage and electrodesiccation.

Bowen,

John T., U.S. dermatologist, 1857-1941.
Bowen disease - a form of intraepidermal carcinoma. Synonym(s): Bowen precancerous dermatosis
bowenoid cells - cells characteristic of Bowen disease.
bowenoid papulosis - a clinically benign form of intraepithelial neoplasia that microscopically resembles Bowen disease or carcinoma in situ, occurring in young individuals of both sexes on the genital or perianal skin usually as multiple well-demarcated pigmented warty papules.
Bowen precancerous dermatosis - Synonym(s): Bowen disease

Bow·en dis·ease

(bō'ĕn di-zēz')
A form of intraepidermal carcinoma characterized by the development of slowly enlarging pinkish or brownish papules or eroded plaques covered with a thickened horny layer.
References in periodicals archive ?
Bowen disease conventionally carries with it the implication of having a strong tendency to recur after local treatment but with only a small percentage progressing to invasive squamous cell carcinoma.
AMSTERDAM -- Topical photodynamic therapy has advanced far enough that it ranks alongside other first-line therapies for actinic keratoses, Bowen disease, superficial basal cell carcinoma, and thin nodular basal cell carcinoma, according to evidence-based guidelines issued by the International Society for Photodynamic Therapy in Dermatology.
Abstract: Clear cell squamous cell carcinoma in situ, also referred to as pagetoid or clear cell Bowen disease, is a rare pathologic variant of this neoplasm.
Bowen disease and risk of subsequent malignant neoplasms: a population-based cohort study of 1147 patients.
AVARIOUS skin problems can cause this appearance but in your age group, and in view of the long history and steady growth of the patch, it is possible you have Bowen Disease.
Basal cell carcinoma Infiltrative, morpheaform, or micronodular histologic subtype Invasion into deep subcutaneous fat, muscle, or cartilage Perineural invasion Positivity of surgical margins Presence of scar within the tumor Squamous cell carcinoma Adenoid, basaloid, small cell or spindle cell histologic subtypes Posttraumatic clinicopathologic subtype Extensive perineural, lymphatic, or vascular invasion Invasion into subcutis Positivity of surgical margins Acantholytic subtype Merkel cell carcinoma Gross size [is greater than] 2 cm Mitotic activity (10 division figures/10 high-power [x400] microscopic fields) Extensive lymphatic or vascular invasion Presence of associated Bowen disease Divergent squamous differentiation in invasive tumor Positivity of surgical margins