Bowen's disease


Also found in: Dictionary, Thesaurus, Legal, Encyclopedia, Wikipedia.
Related to Bowen's disease: squamous cell carcinoma, basal cell carcinoma

Bowen's disease

 [bo´enz]
intraepidermal squamous cell carcinoma, often occurring in multiple sites.

Bowen's disease

Etymology: John T. Bowen, American dermatologist, 1857-1941
a form of intraepidermal carcinoma (squamous cell). It is characterized by red-brown scaly or crusted lesions that resemble a patch of psoriasis or dermatitis. Treatment includes curettage and electrodesiccation. A corresponding lesion found on the glans penis is called erythroplasia of Queyrat. Also called Bowen's precancerous dermatosis.
enlarge picture
Bowen's disease

Bowen's disease

Bowenoid dysplasia, intraepithelial cancer Carcinoma in situ arising in, and confined to, the epithelium

Bowen's disease

A cancer of surface cells (squamous epithelium) which does not extend into the deeper layers but often occurs in several places simultaneously. An intra-epidermal carcinoma. (John Templeton Bowen, 1857–1941, American dermatologist).
Bowen's disease; squamous cell carcinoma in situ premalignant, intraepidermal carcinoma presenting as slow-growing, isolated, slightly raised, well-demarcated, scaly, reddened lesions that may progress to form parakeratotic/crusted irregular plaques, ulcers or squamous cell carcinoma; Bowen's tends to develop within long-term, sun-exposed skin (e.g. face, legs and feet of women); treatment includes surgical excision, cryosurgery or 3-4 weeks' topical application of 5-fluorouracil cream

Bowen's disease

in humans, multiple cutaneous squamous cell carcinomas in situ; reported in dogs and cats. There are hyperkeratotic, hyperpigmented plaques.
References in periodicals archive ?
However, the hallmark of long-term arsenic exposure involves cutaneous changes such as hyperkeratosis, hyperpigmentation, Mee's lines on nails, and malignant skin changes including Bowen's disease, squamous-call carcinoma, and basal-cell carcinoma (Centano et al.
All the patients had Bowen's disease that developed after a long average latency period of 39 years.
1982) reported that of 31 patients with Bowen's disease and increased arsenic levels through drinking water, 10 had invasive skin cancers and 10 had internal malignancies, including 7 patients with pulmonary cancers.
Bowen's disease (squamous-cell carcinoma in situ), which can arise as a consequence of both arsenic and exposure to ultraviolet (UV) radation, seems a natural platform from which to study carcinogenic changes.
Physical examination revealed the presence of cutaneous lesions that had been previously biopsied to show the presence of Bowen's disease.
Moreover, chronic arsenic toxicity should be suspected in anyone presenting with cutaneous changes such as hyperkeratosis, hyperpigmentation, Mee's lines on nails, or malignant skin changes such as Bowen's disease with or without concomitant peripheral neuropathy.
These three amelanotic melanomas were clinically suggestive of Bowen's disease, but careful clinical review identified small areas of pigmentation within the erythematous plaques, noted Dr.
Ernest Allan, Consultant Oncologist at the Christie Hospital said, "The EPISCAN I-200 will help us to accurately asses and treat non-melanoma skin cancers and Bowen's disease by providing high quality images of basal cell carcinoma initial thickness and regression as a result of photodynamic therapy (PDT) treatment.
It is highly effective in the eradication of Bowen's Disease and superficial basal cell carcinomas.