Bouin's fixative

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Related to Bouin's fluid: Bouin's solution, Bouin's fixative

Bouin's fixative

A picric-acid-based compound, which is the fixative of choice for testicular biopsies. It is little used in practice, as it must be removed from tissue before staining with basic dyes and causes DNA methylation, compromising PCR-molecular diagnostics.

Bouin's fixative

a tissue preservative composed of saturated picric acid, formaldehyde and glacial acetic acid. Particularly suitable for trichrome connective tissue stains.