Bouin's fixative

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Related to Bouin's fluid: Bouin's solution, Bouin's fixative

Bouin's fixative

A picric-acid-based compound, which is the fixative of choice for testicular biopsies. It is little used in practice, as it must be removed from tissue before staining with basic dyes and causes DNA methylation, compromising PCR-molecular diagnostics.

Bouin's fixative

a tissue preservative composed of saturated picric acid, formaldehyde and glacial acetic acid. Particularly suitable for trichrome connective tissue stains.
References in periodicals archive ?
After the podia had detached themselves, the coverslips were soaked in Bouin's fluid and prepared for SEM by critical-point drying.
Tissues were fixed in 10% formol saline, Carnoy's fluid, Zenker's fluid, Helly's fluid, and Bouin's fluid, for 24 hours and processed for paraffin wax embedding.