In North America, this zoonosis is associated with 3 species of spirochetes, but most human cases are caused by Borrelia hermsii
, which is found in scattered foci in the western United States and southern British Columbia, Canada (5,6).
Of 39 attendees, 14 (36%) reported fever and at least one of several symptoms associated with the illness (chills, diaphoresis, headache, myalgia, arthralgia, rash, or tick bite) within 7 days after the event; 11 of those had laboratory confirmation of Borrelia hermsii
infection (MMWR 52:809-12, 2003).
Reinfection of vervet monkeys (Cercopithecus aethiops) with Borrelia hermsii
DNA was extracted from the infected liver, and PCR-DNA sequencing of the 16S ribosomal RNA (rRNA) locus identified the bacterium as a relapsing fever spirochete related most closely to Borrelia hermsii
hermsi tick-associated spirochete Spirochaeta hermsi (7), now recognized as Borrelia hermsii
Human disease occurs in many focal areas and is associated with infections of Borrelia hermsii
is the most common cause of tickborne relapsing fever in North America.
Identification and characterization of a linear-plasmid-encoded factor H-binding protein (FhbA) of the relapsing fever spirochete Borrelia hermsii
Partial sequencing of the 16S-23S rDNA intergenic spacer showed two to four genotypes each for Borrelia hermsii
was isolated from the blood of two patients, and Ornithodoros hermsi ticks were collected from the cabin, the first demonstration of this bacterium and tick in Montana.
hermsi were first named Spirochaeta hermsi in 1942 and later changed to Borrelia hermsii
Population structure of the relapsing fever spirochete Borrelia hermsii
as indicated by polymorphism of two multigene families that encode immunogenic outer surface lipoproteins.