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Borna disease
(redirected from Borna virus)

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Borna disease
a geographically restricted virus disease of horses and occasionally sheep, characterized by a uniformly fatal encephalomyelitis. Clinically it is characterized by pharyngeal paralysis, muscle tremor, lethargy and flaccid paralysis. The causative virus is a non-segmented, negative-stranded RNA virus with a nuclear site of replication and transcription of its genome. It is noncytolytic and highly neurotropic and is the prototype and only member thus far identified of the family Bornaviridae, in the order Mononegavirales. Serologic evidence indicates that the host range of Borna disease virus or an antigenically related virus is wide and the virus has been linked to psychiatric illnesses in humans. Called also Near Eastern equine encephalomyelitis.
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Behavioral disease in rats caused by immunopathological responses to persistent borna virus in the brain.
Shrews as reservoir hosts of Borna disease virus by Ehrensperger, Felix / Emerging Infectious Diseases
Two German virologists, Liv Bode and Hanns Ludwig, who have studied the Borna virus extensively, believe that the virus infects humans as well as horses and other animals.
"It kills horses, doesn't it?" by Brown, Edwin W. / Medical Update
Bode and his colleagues obtained the Borna virus from three people who had been diagnosed with mood disorders.
Is mental illness infectious by Science News
 
 
 
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