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Borna disease
(redirected from Borna disease virus)

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Borna disease
a geographically restricted virus disease of horses and occasionally sheep, characterized by a uniformly fatal encephalomyelitis. Clinically it is characterized by pharyngeal paralysis, muscle tremor, lethargy and flaccid paralysis. The causative virus is a non-segmented, negative-stranded RNA virus with a nuclear site of replication and transcription of its genome. It is noncytolytic and highly neurotropic and is the prototype and only member thus far identified of the family Bornaviridae, in the order Mononegavirales. Serologic evidence indicates that the host range of Borna disease virus or an antigenically related virus is wide and the virus has been linked to psychiatric illnesses in humans. Called also Near Eastern equine encephalomyelitis.
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In The Neurobiology of Autism (Bauman and Kemper 2005), the authors draw parallels in neurobiology and behavior with autism and another type of infection, neonatal Borna disease virus.
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Borna disease virus (BDV) is the causative agent of Borna disease, a meningoencephalitis of horses and sheep in central Europe (1).
Novel Borna virus in Psittacine birds with proventricular dilatation ... by Honkavuori, Kirsi S.; Shivaprasad, H.L.; Williams, Brent L.; Quan, Phenix-Lan; Hornig, Mady; Street, / Emerging Infectious Diseases
Among the chapter topics are psychosocial and environmental formulations, monoaminergic-based pharmacotherapy, pyschobiology of electroshock, depression and suicidality in children and adolescents, the biology and genetics of suicidality, depression in the context of cancer, stress system dysregulation, neuroimmune mediators, Borna disease virus, animal models, and depression and heart disease.
Biology of Depression: From Novel Insights to Therapeutic Strategies, ... by SciTech Book News
 
 
 
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