Mutation in bone morphogenetic protein receptor-IB is associated with increased ovulation rate in Booroola Merino
The mutation is closely linked to the high prolificacy of Booroola Merino ewes, and the A746G mutation of the BMPR-IB gene located at chromosome 6 has been defined as FecB (Mulsant et al.
Existing studies have verified the existence of the FecB mutation in some world-renowned species with high fertility such as Booroola Merino in Australia (Mulsant, 2001; Wilson, 2001), the Garole in India (Davis et al.
A few producers in the United States are using AI to introduce genes from foreign breeds like the Booroola Merino
Only five Booroola Merino
rams as foreign genetic material was introduced once in 1986, except this exotic rams, the replacement were selected from the same flock for several decades, which lead to increase the inbreeding that play a vital role in manifestation of undesired recessive traits, Shamir et al.
The FecB gene is a dominant autosomal gene responsible for the fecundity of Booroola Merino sheep with an additive effect on ovulation rate firstly identified in 1980s (Piper et al.
The single gene inheritance of the high litter size of the Booroola Merino.
Numbers of steroidogenic luteal cells in Booroola Merino
A non-conservative substitution (Q249R) in the intracellular kinase domain of bone morphogenetic protein receptor IB (BMPR-IB) was found to be fully associated with the increased ovulation rate of highly prolific Booroola Merino sheep (Mulsant et al.
The Q249R mutation in Booroola Merino sheep was not detected in chickens.