BMP15

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BMP15

A gene on chromosome Xp11.2 that encodes bone morphogenetic protein 15, which is thought to play a role in oocyte and follicular development.
References in periodicals archive ?
Growth differentiation factor 9 and bone morphogenetic protein 15 (BMP15) are two oocyte-specific proteins and co-expressed by growing oocytes in rodents, sheep, and humans (1-3).
Oocyte expression, secretion and somatic cell interaction of mouse bone morphogenetic protein 15 during the peri-ovulatory period.
Among the factors secreted by the oocyte, we highlight members of the transforming growth factor beta (TGF-[beta]) superfamily and, among these, the growth and differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15), which are expressed in all stages of follicular development in the bovine species and are involved in controlling the proliferation and steroidogenesis of granulosa cells (Juengel and McNatty, 2005).
The bone morphogenetic protein 15 gene is X-linked and expressed in oocytes.
Expression of bone morphogenetic protein 15 (BMP-15) during In vitro maturation in canine oocytes.
Three of these Fec genes identified in sheep are bone morphogenetic protein receptor type IB (BMPRIB) or Activin Like Kinase 6, known as FecB located on chromosome 6;[3,4,5] growth differentiation factor (GDF9), known as FecG located on chromosome 5 [6,7] and bone morphogenetic protein 15 (BMP15), known as FecX located on the X chromosome the full lenght.
Key Words: Bone morphogenetic protein 15, BMP15, polymorphisim, nucleotide aligment.
A new candidate gene, bone morphogenetic protein 15 (BMP15) has been investigated in POF.
By promoting granulosa cell mitosis, bone morphogenetic protein 15 inhibits the expression of the follicle-stimulating hormone receptor in granular cells, and adjusts their proliferation and differentiation.
One of the latest members of this super family is Bone Morphogenetic protein 15 (BMP15) or GDF9B [3,4,10].
2004); and bone morphogenetic protein 15 (BMP15) known as FecX on chromosome X (Hanrahan et al.
In 1998 two groups independently described the bone morphogenetic protein 15 (BMP15), also known as growth and differentiation factor 9B (GDF9B), in the mouse ovary.

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