bone marrow aspiration

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bone marrow aspiration

Removal of bone marrow fluid via a needle to diagnose a number of conditions, including leukemia, lymphoma, and multiple myeloma. Bone marrow aspiration is also used for bone marrow transplantation. See bone marrow transplantation.

bone marrow

the soft, organic material in the cavities of bones, a network of blood vessels and special connective tissue fibers that hold together a composite of fat and blood-producing cells.
The chief function of bone marrow is to manufacture erythrocytes, leukocytes and platelets. These blood cells normally do not enter the bloodstream until they are fully developed, so that the bone marrow contains cells in all stages of development. If the body's demand for white cells is increased because of infection, the bone marrow responds immediately by increasing production. The same is true if more red blood cells are needed, as in hemorrhage or anemia.
There are two types of bone marrow, red and yellow. The former produces the blood cells; the latter, which is mainly formed of fatty tissue, normally has no blood cell-producing function.

bone marrow aplasia
any of the three cell lines may be singularly aplastic but a pancytopenic abnormality is most common. See also aplastic anemia.
bone marrow aspiration
see bone marrow biopsy.
congenital bone marrow hypoplasia
bone marrow-derived cells
see B lymphocyte.
bone marrow displacement
bone marrow dyscrasia
abnormal cell production by the bone marrow. Occurs in some dog breeds, especially Poodles, in which there are maturation abnormalities of erythrocytes with macrocytosis and hypersegmented neutrophils.
bone marrow spaces
the cavities in cancellous bone that are usually filled with bone marrow.
bone marrow suppression
some drugs and infectious agents can cause reduced erythropoiesis, myelopoiesis and megakaryocytopoiesis. See also anemia, pancytopenia.
toxic bone marrow arrest
see resurgence granulopoiesis.
bone marrow transplantation
the transfer of bone marrow from a normal, antigenically matched individual to another, usually for treatment of aplastic anemia, immunodeficiency or metabolic disorders.
References in periodicals archive ?
At this point of time, bone marrow examination showed no evidence of lymphomatous infiltration.
Bone marrow examination showed erythroid hyperplasia and macrophages with hemophagocytosis and with gametocyte form of P.
Zinc-induced copper deficiency: a report of three cases initially recognized on bone marrow examination.
A bone marrow examination reveals the presence of the Philadelphia chromosome (the same translocation seen in CML) or a variety of other translocations or complex genetic abnormalities.
A pathologist's perspective on bone marrow aspiration and biopsy, I: performing a bone marrow examination.
Abundant blasts were observed on the peripheral smear and bone marrow examination.
They showed a higher diagnostic yield when bone marrow examination and peripheral blood culture were used in parallel.
Patients are considered to be in remission if a bone marrow examination finds cancer cells account for fewer than five in 100 cells.
Bone marrow examination and molecular analysis were performed 3 times-8 weeks after the commencement of ATRA therapy, and 6 weeks and 22 weeks after the third consolidation chemotherapy--and showed complete hematological and molecular remission with undetectable PML-RAR[alpha].
A complete blood count (CBC) and bone marrow examination need to be run to evaluate a suspected person with sickle cell anemia initially.
Bone marrow examination findings demonstrated severe hypoplasia of all three lineages without fibrosis.
In the second case, the very short latency period between the diagnosis of the NHL and the occurrence of the secondary malignancy as well as the discrete bone marrow changes at the bone marrow examination after occurrence of bicytopenia raised the suspicion of tMDS.

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