osteocalcin

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Related to Bone GLA Protein: matrix Gla protein, BGLAP

os·te·o·cal·cin

(os'tē-ō-kal'sin),
A protein found in osteoblasts and dentin; contains γ-carboxyglutamyl residues; has a role in mineralization and calcium ion homeostasis.
Synonym(s): bone Gla protein

osteocalcin

(ŏs′tē-ō-kăl′sĭn)
n.
A calcium-binding substance produced by osteoblasts that is essential to bone mineralization and can be used as a biomarker for osteoporosis. It may also act as a hormone to increase insulin production and insulin sensitivity.

osteocalcin

[-kal′sin]
a protein found in the extracellular matrix of bone and dentin and involved in regulating mineralization in the bones and teeth.

BGLAP

A gene on chromosome 1q25-q31 that encodes a protein which constitutes 1–2% of bone protein, which binds strongly to apatite and calcium.

os·te·o·cal·cin

(os'tē-ō-kal'sin)
Protein found in osteoblasts and dentin.

osteocalcin (os´tēōkal´sin),

n vitamin Kdependent calcium-binding protein synthesized by osteoblasts and found primarily in bone. Serum osteocalcin measurements provide a noninvasive specific marker of bone metabolism.

osteocalcin

a product of the resorption of bone.
References in periodicals archive ?
Vitamin K is a cofactor of [gamma]-carboxylase, which converts three glutamic acid (Glu) residues to [gamma]-carboxyglutamic acid (Gla) and, thus, is essential for y-carboxylation of the bone GLA protein OC (Ferland, 1998; Stafford, 2005).
Bone Gla protein (osteocalcin) assay standardization report.
Abnormal serum bone Gla protein levels in multiple myeloma: crucial role of bone formation and prognostic implications.