Bohr effect

effect /ef·fect/ (ĕ-fekt´) the result produced by an action.

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Anrep effect  abrupt elevation of aortic pressure results in a positive inotropic effect, augmented resistance to outflow in the heart.

Bayliss effect  increased perfusion pressure and subsequent stretch of vascular smooth muscle causes muscle contraction and increased resistance, which returns blood flow to normal in spite of the elevated perfusion pressure.

Bohr effect  increase of carbon dioxide in blood causes decreased affinity of hemoglobin for oxygen.

Doppler effect  the relationship of the apparent frequency of waves, as of sound, light, and radio waves, to the relative motion of the source of the waves and the observer, the frequency increasing as the two approach each other and decreasing as they move apart.

experimenter effects  demand characteristics.

Haldane effect  increased oxygenation of hemoglobin promotes dissociation of carbon dioxide.

position effect  in genetics, the changed effect produced by alteration of the relative positions of various genes on the chromosomes.

pressure effect  the sum of the changes that are due to obstruction of tissue drainage by pressure.

side effect  a consequence other than that for which an agent is used, especially an adverse effect on another organ system.

Somogyi effect  a rebound phenomenon occurring in diabetes: overtreatment with insulin induces hypoglycemia, which initiates the release of epinephrine, ACTH, glucagon, and growth hormone, which stimulate lipolysis, gluconeogenesis, and glycogenolysis, which, in turn, result in a rebound hyperglycemia and ketosis.

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Bohr effect

n.

The influence of carbon dioxide on the oxygen dissociation curve of blood. The shift of the curve to the right means a reduction in the affinity of hemoglobin for oxygen.

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Bohr effect

Etymology: Christian Bohr, Danish physiologist, 1855-1911

the effect of CO₂ and H⁺ on the affinity of hemoglobin for molecular O₂. Increasing PCO₂ and H⁺ decrease oxyhemoglobin saturation, whereas decreasing concentrations have the opposite effect. In humans a decrease of pH from 7.4 to 7.3 at 40 mm Hg PO₂ decreases oxyhemoglobin saturation by 6%. The Bohr effect is particularly significant in the capillaries of working muscles and the myocardium and in maternal and fetal exchange vessels of the placenta.

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Bohr effect

displacement of the oxyhemoglobin dissociation curve by a change in carbon dioxide tension.