Blue Cell Tumour

A usually malignant tumour, the cells of which are arranged in nests, sheets, and masses, and composed of relatively monotonous, round-to-oval, 8–15-µm in diameter cells with poorly defined cytoplasmic borders and strongly basophilic—blue—by H&E staining nuclei; embryologic origin often requires ancillary information provided by histologic pattern, immunohistochemistry, and rarely electron microscopy
DiffDx
Children Neuroblastoma, Ewing sarcoma, NHL, embryonal rhabdomyosarcoma
Adults Neuroendocrine tumour, mesenchymal chondrosarcoma, hemangiopericytoma, large cell lymphomas, Merkel cell tumour, small cell osteosarcoma, small/oat cell carcinoma, alveolar rhabdomyosarcoma
References in periodicals archive ?
Microscopy revealed a highly necrotic and malignant small blue cell tumour.
Pathological and radiological differential diagnosis Small round blue cell tumour Radiological Non-Hodgkin's lymphoma Rhabdomyosarcoma Rhabdomyosarcoma Myosarcoma Small cell lung cancer Malignant fibrous Merkel cell cancer histiocytoma (MFH) Haemangiopericytoma Dedifferentiated liposarcoma Neuroblastoma Ewing's sarcoma Ewing's sarcoma Primitive neuro-ectodermal tumour (PNET)
Both Ewing's sarcoma and ESS are confirmed by features on histological analysis and should be differentiated from other round blue cell tumours and members of the Ewing's family of tumours.