central fatigue

(redirected from Blood-Glucose Bonk)
Mental fatigue that develops during prolonged exercise and is attributed to impaired function of the central nervous system; central fatigue may correlate with a buildup of tryptophan, causing sleepiness and mental fatigue

central fatigue

contribution of the central nervous system to the overall condition of fatigue in physical activity. Mainly significant in prolonged exercise, such as marathon running, where voluntary effort declines before muscle glycogen is exhausted and other peripheral indicators (heart rate, blood lactate, blood glucose, etc.) do not suggest particular stress. There is evidence that elevated serotonin (5-HT) and/or reduced dopamine levels in the brain are involved.