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blood substitute

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blood substitute,
a substance used for a replacement or volume expansion for circulating blood. Plasma, human serum albumin, packed red cells, platelets, leukocytes, and concentrates of clotting factors are often administered in place of whole blood transfusions in the treatment of various disorders. Substances that are sometimes used to expand blood volume include dextran, hetastarch, albumin solutions, or plasma protein fraction. Perfluorocarbon emulsions, although potentially toxic, have been tested as blood substitutes; they are able to carry oxygen to tissues, have a long shelf life without refrigeration, and do not induce antigen-antibody reactions.


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Among the blood substitutes at issue are those made by Northfield Laboratories of Evanston, IL, and Biopure of Cambridge, MA.
Blood-substitute review faults FDA by Adverse Event Reporting News
An ideal blood substitute would eradicate the risk of disease transmission, most notably HIV and hepatitis; be compatible with all blood types; have a shelf life approximately four times that of donated human blood; and prove hugely beneficial in cases of trauma--at home or on the battlefield--as well as for transfusions during surgery.
Viable human blood substitute found? by USA Today (Magazine)
Creating a blood substitute conjures up another fascinating puzzle.
The case of the missing donations by Bersch, Carren / Medical Laboratory Observer
 
 
 
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