Blast cells


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Blast cells

Blood cells in early stage of cellular development.

blast

1. an immature stage in cellular development before appearance of the definitive characteristics of the cell; used also as a word termination, as in ameloblast, etc.
2. the wave of air pressure produced by the detonation of high-explosive bombs or shells or by other explosions; it causes pulmonary damage and hemorrhage (lung blast, blast chest), laceration of other thoracic and abdominal viscera, ruptured eardrums, and effects in the central nervous system.

blast cells
the precursor cells of bone marrow. See also myeloblast, monoblast, erythroblast, megakaryoblast.
References in periodicals archive ?
The number of blast cells in the peripheral blood should be subtracted from the number of blasts in the CSF and the blasts in the CSF reported as two percent.
To monitor the further development of the patient's disorder, a complete automated blood cell count and a differential cell count were performed almost every day until disappearance of blast cells and other atypical cells.
The building includes approximately 17,000 square feet of rack support freezer, four blast cells, 37,000 square feet of climate controlled manufacturing and warehouse areas, and approximately 10,000 square feet of racked ambient storage warehouse.
9]/L, and no evidence of leukemia in other sites); nonresponder (NR; cellular marrow with >5% blast cells or evidence of leukemia in other sites, after at least two courses of chemotherapy); and early relapse (ER; relapse within 6 months from remission) (21).
No blast cells were identified in the peripheral smear.
The new freezers will maintain temperatures -10 [degrees] F and the blast cells will operate at -30 [degrees] F.
The red cell count should be low, since the presence of many blast cells in the bone marrow tends to crowd them out.
The most dramatic improvement in overall survival was seen in 19 patients who also showed either bone marrow complete response (CR) or initial >50% decrease in blast cells (Abstract #3998).
Cases with <20% blast cells may still be diagnosed as acute leukemia if they present with certain recurrent cytogenetic abnormalities, as in AML M4 with inv (16) or t (16;16) (p13;q22) and AML M2 with t (8), (21)
The clinical study also measured intracellular uptake of LOR-2040 in the bone marrow leukemic cells, and identified significant accumulation of the drug in the bone marrow blast cells and suggested preferential uptake of the drug by CD34+ cells, an important malignant bone marrow cell population.