Black Liver Disease

A popular term for a rare autosomal recessive [MIM 237500] condition which is asymptomatic, and characterised by a blackened liver caused by defective conjugated bilirubin excretion; bilirubin levels are usually 120 µmol/L—US 7 mg/dl—60% conjugated—direct; estrogens should be avoided as they may intensify the jaundice
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