Biphosphonates

Biphosphonates

Compounds (like alendronate) that slow bone loss and increase bone density.
Mentioned in: Osteoporosis
References in periodicals archive ?
Par ailleurs, d'autres produits alternatifs pour la prise en charge de certaines pathologies frequentes feront partie de cette septieme liste additive, il s'agit entre autres, des antithrombotiques, utilises dans le traitement et la prevention primaire et/ou secondaire dans diverses indications cardio-vasculaires, les antiviraux indiques dans le traitement de l'hepatite B, les biphosphonates indiques dans le traitement de l'osteoporose de l'osteopenie et de la maladie de Paget(affection chronique des os), ainsi que les antianemiques indiques dans le traitement de l'anemie d'origine renale .
Biphosphonates in the treatment of thalassemia-induced osteoporosis.
There are many different therapies including biphosphonates which can decrease loss of bone and decrease fracture risk in patients who already have had sustained a fracture.
Calcitonin acts by decreasing bone turnover, while biphosphonates inhibit bone resorption and suppress IL-1[beta], IL-6, and TNF-[alpha] secretion.
Beside adequate hydration and diuresis, calcitonin or biphosphonates are the other medical treatment options.
However, antiproliferative effects related to MMP inhibition of biphosphonates in atherosclerosis, which is also a proliferative process remains unclear.
Discussion of osteoporosis drugs currently on the market in six major classes: biphosphonates, selective estrogen receptors modulators (SERMs), calcitonins, parathyroid hormones, dual-action bone agents, and hormone replacement therapies (HRTs)
In addition to the corrections in living conditions, exercise, reducing smoking and alcohol consumption, and calcium and vitamin D supplements; the biphosphonates have become an indispensible part of the treatment to prevent these events with their benefits demonstrated in various studies in the recent years.
Merrion Pharma currently has four internal product development projects: two oral biphosphonates, Orazol (MER 101) and Almerol (MER 103); MER 102; and Acyline (MER 104).
Biphosphonates, such as disodium pamidronate, alendronate sodium, and risedronate sodium, are used in the treatment of osteoporosis.
Washington, Apr 20 (ANI): A new study has revealed that treatment with biphosphonates could prevent radiation-induced leukaemia.