bioassay

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bioassay

 [bi″o-as´a]
determination of the active power of a drug sample by comparing its effects on a live animal or an isolated organ preparation with those of a reference standard.

bi·o·as·say

(bī'ō-as'ā),
Determination of the potency or concentration of a compound by its effect on animals, isolated tissues, or microorganisms, as compared with an analysis of its chemical or physical properties.

bioassay

/bio·as·say/ (bi´o-as″a) determination of the active power of a drug sample by comparing its effects on a live animal or an isolated organ preparation with those of a reference standard.

bioassay

(bī′ō-ăs′ā′, -ă-sā′)
n.
1. Determination of the strength or biological activity of a substance, such as a drug, by comparing its effects with those of a standard preparation on a test organism.
2. A test used to determine such strength or activity.
tr.v. bioas·sayed, bioas·saying, bioas·says
To cause to undergo a bioassay.

bioassay

[bī′ō·as′ā, -əsā′]
Etymology: Gk, bios + Fr, assayer, to try
the laboratory determination of the concentration of a drug or other substance in a specimen by comparing its effect on an organism, an animal, or an isolated tissue with that of a standard preparation. Also called biological assay.

bioassay

Lab medicine
Any quantification procedure to detect:
(1) The activity or potency—functional or effective—amount of a substance—e.g., antibiotic, chemical, drug, hormone, metabolit, vitamin, etc.—in a biological fluid;
(2) Toxicity of a substance (e.g., a pollutant) or organism (e.g., a pathogen) of interest in an in vivo system, i.e., in a cell or animal; in bioassays, the effect is tested on living cells or organisms.
 
Molecular biology
An assay that uses a living system, such as an intact cell, to measure an effect or a molecule of interest.
 
Radiation physics
A determination of the quantity of radioactive material in the human body, either by direct measurement—in vivo counting—or by analysis of excreta.

bi·o·as·say

(bī'ō-as'ā)
Determination of the potency or concentration of a compound by its effect on animals, isolated tissues, or microorganisms, as contrasted with analysis of its chemical or physical properties.
Synonym(s): biologic assay, biotest.

bioassay

A method of measuring the potency of a drug or other biochemical agent by comparing its effects on animals with those of known preparations of standard strength.

bioassay

determination of the active power of a drug sample by comparing its effects on a live animal or an isolated organ preparation with those of a reference standard.
References in periodicals archive ?
CDC bottle bioassays were used to assess insecticide susceptibility in field collected Aedes albopictus.
The bioassay followed a modified "maximum challenge test" methodology, which is useful for separating virulent from non-virulent isolates at the early stages of entomopathogen screening programmes (10).
Table 1: Incorporating New Technologies into Bioassay Development
This effect has also been reported in eggs of Roduviidao, where the application directly on the chorion was the most successful ovicidal action in bioassays conducted by CARNEIRO et al.
The consistency of the mAb/ligand interaction is supported by the fact that the (inhibition) bioassay gave virtually identical results for all originator lots as well as all biosimilar candidates.
Thus, the values of the cell densities of cyanobacteria proposed by this legislation served as a guideline for the concentrations used for the bioassays in this work because the term "bloom" is not well defined and is generally described as being a phytoplankton biomass significantly higher than the average of the water body in question (Zohary and Roberts, 1990).
Comparison with topical application and dip bioassay, which are the generally which are generally used as bioassays for monitoring resistance to aphids, glass tube residual film bioassay is more simple, though not as accurate as topical application bioassay (Huang et al.
The last bioassay on each replication was run 8 days after the initial application of malathion, but survival levels on control plates on the last bioassay was not different from that of the first or second bioassays in each replication ([r.
Cisbio Bioassays is a global developer of products and technologies used in in vitro diagnostics and assay development for drug screening procedures.
Four of the bioassays were performed in a growth room where only the photoperiod (12:12 h) and the luminosity (592 [+ or -] 2.
Bench-top" bioassays for the discovery of bioactive natural products: an update, Proceeding of the Eighth National Seminar and Unesco Regional Workshop on the Bioassay of Natural Products with Special Emphasis on Anticancer Agents, pp.
Thus, bioassays that reveal the overall androgen bioactivity of complex mixtures would be more appropriate tools with great implications in antidoping analysis (6-8).