BioGlue

A proprietary—CryoLife—adhesive used to repair aortic dissections, seal vessels, and reconstruct and reinforce peribronchial soft tissue to decrease air leaks
Composition Bovine serum albumin and glutaraldehydeare dispensed via a double-chambered syringe. Once dispensed, the adhesive components mix within the applicator tip where the cross-linking begins (within 20 to 30 seconds; it reaches bond strength within 2 minutes). The glutaraldehyde molecules bond with the BSA molecules creating a flexible mechanical seal independent of the body's clotting mechanism.
References in periodicals archive ?
Cerebrospinal fluid leak rate after the use of BioGlue in translabyrinthine vestibular schwannoma surgery: a prospective study.
The company said the increase was primarily driven by increases in tissue processing, BioGlue, On-X and TMR revenues, partially offset by the absence of HeRO revenues.
Contract Awarded for Cryolife Bioglue Adhesive - Mpls Va
Treatment of splenic injury during laparoscopic nephrectomy with BioGlue, a surgical adhesive.
Additionally, the company has collected about USD3m in revenue in 2014 from the sale of BioGlue, PerClot, and BioFoam to its French distributor.
Bioglue (glutaraldehido, albumina bovina [Cryolife, Kennesaw, Georgia, EE.
The abnormal diaphragmatic surface was sealed with bioglue, and a vascularized parietal pleural flap was created and tacked over the diaphragm with permanent suture (Figure 4).
CryoLife, Inc, Atlanta, GA, announced that its BioGlue Surgical Adhesive has received Shonin approval from the Japanese Ministry of Health, Labor and Welfare (MHLW) for use in the repair of aortic dissections.
With the help of micro-manipulation technique, the researchers measured the force needed to overcome the bioglue adhesion, and showed that dried biofilm stuck 20-times more tightly than fresh biofilm.
The company's BioGlue Surgical Adhesive is FDA approved as an adjunct to sutures and staples for use in adult patients in open surgical repair of large vessels.
BioGlue is also CE marked in the European Community and approved in Canada for use in soft tissue repair and in Australia for use in vascular and pulmonary sealing and repair.
BioGlue is a two-component adhesive composed of purified bovine serum albumin (BSA) and glutaraldehyde.