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binding site

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia, Hutchinson 0.04 sec.
site (sīt) a place, position, or locus.
allosteric site  a site on a multi-subunit enzyme that is not the substrate binding site but that when reversibly bound by an effector induces a conformational change in the enzyme, altering its catalytic properties.
antigen-binding site , antigen-combining site the region of the antibody molecule that binds to antigens.
binding site  in an enzyme or other protein, the three-dimensional configuration of specific groups on specific amino acids that binds specific compounds, such as substrates or effectors, with high affinity and specificity.
operator site  a site adjacent to the structural genes in the operon, where repressor molecules are bound, thereby inhibiting the transcription of the genes in the adjacent operon.
restriction site  a base sequence in a DNA segment recognized by a particular restriction endonuclease.

binding site
Etymology: ME, binden + L, situs
the location on the surface of a cell or a molecule where other cell fragments or molecules attach to initiate a chemical or physiologic action.

binding site,
n the location on the surface of a cell or molecule where other cell fragments or molecules attach to initiate a chemical or physiologic action.

Patient discussion about binding site.

Q. My friend has Progressive MS, he is bound to a wheelchair, Prognosis? How can I help? He must be moved by a Hoyer Lift, he has caregivers. He has a beautiful voice and does have enough ability to move in his chair around local community. He has some bad days with spacicity, I want to help but am unsure as to how? He is 60? or so and lives on his own, he has had MS for many years and a number of complications, such as pneumonia and decubitus. Please help me to help him!

A. There are a number of ideas and resources for social and recreational activities (i.e. wheelchair sports, dancing, travel, aviation, etc.) that may be helpful, which can be found at www.mobility-advisor.com.

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? Mentioned in ? References in periodicals archive
 
Viral particles bind specifically to digestive ducts (midgut, main and secondary ducts, and tubules) by carbohydrate structures with a terminal N-acetylgalactosamine residue in an [alpha] linkage (same binding site used for recognition of human histo-blood group antigens).
This result indicated that the common binding site was a nonclassical membrane estrogen receptor.
On human chromosome 2, RUNX1 fits into a binding site that lies in the middle of a gene called programmed cell death 1, or PDCD1.
 
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