association constant

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as·so·ci·a·tion con·stant

1. in experimental immunology, a mathematical expression of hapten-antibody interaction: average association constant, K = [hapten-bound antibody]/[free antibody][free hapten];
2. the equilibrium constant involved in the association of two or more compounds or ions into a new compound; the reciprocal of the dissociation constant.
Synonym(s): binding constant
References in periodicals archive ?
In a recent communication appearing in the Journal of the Americal Chemical Society (2004, 126, 5030), a synthetic receptor featuring 8 hydrogen bonding groups is reported that has binding constants for sulfate exceeding [10.
From the temperature dependence of the binding constant, it is possible to estimate the values for the thermodynamic functions involved in the binding process.
a] values and the glucose equilibrium binding constants of the amidated derivatives of the boronic acid species bound to the hydrogel.
8,921,299 B2; The Procter & Gamble Company has patented a detergent composition comprising tiron (1,2-dihydroxybenzene-3,5-disulfonic acid, or mono- or di-sulfonate salts of the acid); a ligand capable of chelating to Fe3+, wherein the ligand has a binding constant for Fe3+ that is greater than 1018 M-1, and wherein the ligand is selected from the group consisting of aminocarboxylates containing at least two N atoms, amino-phosphonates containing at least two N atoms, and geminal bisphosphonates; an iron-displacing species selected from the group consisting of phenyl boronic acid, A13+' and mixtures thereof; and at least about 0.
In addition, D-penicillamine binding constant is high enough that transfer of toxic minerals at cell junctions does not occur.
A solvent also plays a significant role in governing the magnitude of the binding constant.