Bile ducts

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Related to Bile ducts: common bile duct, Intrahepatic bile ducts


a clear yellow or orange fluid produced by the liver. It is concentrated and stored in the gallbladder, and is poured into the small intestine via the bile ducts when needed for digestion. Bile helps in alkalinizing the intestinal contents and plays a role in the emulsification, absorption, and digestion of fat; its chief constituents are conjugated bile salts, cholesterol, phospholipid, bilirubin, and electrolytes. The bile salts emulsify fats by breaking up large fat globules into smaller ones so that they can be acted on by the fat-splitting enzymes of the intestine and pancreas. A healthy liver produces bile according to the body's needs and does not require stimulation by drugs. Infection or disease of the liver, inflammation of the gallbladder, or the presence of gallstones can interfere with the flow of bile.
bile acids steroid acids derived from cholesterol; classified as primary, those synthesized in the liver, e.g., cholic and chenodeoxycholic acids, or secondary, those produced from primary bile acids by intestinal bacteria and returned to the liver by enterohepatic circulation, e.g., deoxycholic and lithocholic acids.
bile ducts the canals or passageways that conduct bile. There are three bile ducts: the hepatic duct drains bile from the liver; the cystic duct is an extension of the gallbladder and conveys bile from the gallbladder. These two ducts may be thought of as branches that drain into the “trunk,” or common bile duct. The common bile duct passes through the wall of the small intestine at the duodenum and joins with the pancreatic duct to form the hepatopancreatic ampulla, or ampulla of Vater. At the opening into the small intestine there is a sphincter that automatically controls the flow of bile into the intestine.

The bile ducts may become obstructed by gallstones, benign or malignant tumors, or a severe local infection. Various disorders of the gallbladder or bile ducts are often diagnosed by ultrasonography, radionuclide imaging, and x-ray examination of the gallbladder and bile ducts using a special contrast medium so that these hollow structures can be clearly outlined on the x-ray film.

Bile ducts

Tubes that carry bile, a thick yellowish-green fluid that is made by the liver, stored in the gallbladder, and helps the body digest fats.
References in periodicals archive ?
Our experienced clinical team combined with calculated investment has enabled us to advance development of this treatment, which, because of its application, has the potential for use among a range of rare and difficult to treat cancers like mesothelioma and bile duct cancer.
Package 31 - self-expanding prosthesis to the bile ducts for the treatment of neoplastic lesions.
A seven-year-old girl who was suffering from sickle cell anemia had a serious medical complication where an accumulation of stones in her gall bladder blocked the bile duct causing the bile to rise to dangerous levels.
Primed Th1 lymphocytes would then orchestrate an immune response by releasing proinflammatory cytokines and recruiting cytotoxic T cells, ultimately resulting in damage to bile ducts and liver parenchyma.
A 34-year-old woman presented with a history of a previous laparoscopic cholecystectomy, followed within a few days by a formal laparotomy for a suspected bile duct injury.
Ms Dodgson, who lives in Blackwood with her seven-year-old son, was transferred to the Queen Elizabeth Hospital in Birmingham for surgery to reconstruct her bile duct.
Over the previous year, we carefully interviewed 66 consecutive patients using a standardized questionnaire asking about their exposure to asbestos and other known risk factors linked to bile duct carcinogenesis (Khan et al.
It also allows them to take biopsies and to treat blockages due to cancers and gallstones in the bile duct.
If major bile ducts are obstructed, surgery or therapeutic endoscopy may be required, but should be avoided in parenchymal liver disease as inappropriate intervention may aggravat the situation.
They may be coiled and, if multiple, may completely fill the bile duct, which produces either the "spaghetti sign," or, if they are very densely packed in the bile ducts, may appear amorphous and manifest as hyperechoic pseudotumors.
Since biliary malignancies often affect the bile ducts through obstruction, the most common finding is an obstructed, dilated bile duct.
ERCP is a specialized endoscopic procedure that is performed with fluoroscopy and contrast injection to examine and treat conditions of the bile ducts and pancreas, such as removing gallstones, opening obstructed bile ducts, and obtaining biopsies in suspected tumors.