bile acid

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bile acid

/bile ac·id/ (bīl as´id) any of the steroid acids derived from cholesterol; classified as primary, those synthesized in the liver, e.g., cholic and chenodeoxycholic acids, or secondary, those produced from primary bile acids by intestinal bacteria, e.g., deoxycholic and lithocholic acids. Most of the the bile acids are reabsorbed and returned to the liver via the enterohepatic circulation. Cf. bile salt under salt.

bile acid

n.
Any of the liver-generated steroid acids, such as cholic acid, that commonly occur in the bile in combination with glycine and taurine as sodium salts.

bile acid

a steroid acid of the bile, produced during the metabolism of cholesterol. On hydrolysis, bile acid yields glycine and choleic acid.

bile acid

Either of several acids—e.g., cholic acid (CA), chenodeoxycholic acid (CDA)—which are formed in the liver and converted by intestinal bacteria into deoxycholic acid (from CA) and lithocholic acid (from CDA), which are known as secondary BAs. BAs are conjugated in the liver to glycine or taurinese conjugates; glycocholic acid and taurocholic acid form sodium and potassium salts in the alkaline bile in the liver. These conjugated bile acids have a central role in the emulsification and absorption of fatty acids.

Specimen
Serum.
 
Ref range
< 60 µg/mL—as cholylglycine.
 
Method
RIA.