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bicalutamide |
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bicalutamide /bi·ca·lu·ta·mide/ (bi?kah-loo´tah-mid) an antiandrogen used in the treatment of prostatic carcinoma. |
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? Mentioned in | ? References in periodicals archive | |
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Four laboratories received four coded compounds and two controls: two steroidal androgens, two antiandrogens, an androgenic control, 5[alpha]-dihydrotestosterone (DHT), and an antiandrogenic control, bicalutamide (ICI 176,334). The first study, conducted by McLeod on 255 patients, compared Abarelix with the combination of leuprolide and bicalutamide, the current hormonal therapy. The use of bicalutamide has significantly decreased in localized stage between 2003 and 2005 since the EPC trial demonstrated increased mortality with bicalutamide 150mg. |
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