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valdecoxib |
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valdecoxib /val·de·cox·ib/ (val?de-kok´sib) a nonsteroidal antiinflammatory drug of the COX-2 inhibitors group, used for the treatment of osteoarthritis, rheumatoid arthritis, and primary dysmenorrhea. |
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And physicians are becoming more leery of thinking that every new drug represents a 'breakthrough' or improvement over existing therapies--something that resulted in part from the problems around Vioxx and Bextra," she said. And it recommends a "black box warning"--the most serious possible--on the detailed package insert of all three Cox-2 drugs: Vioxx, Celebrex and Bextra. Based on this, Vioxx and Bextra may be associated with a higher risk of a heart attack because they are more potent inhibitors of COX-2 enzymes than Celebrex. |
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