Betafectin


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Betafectin

A recombinant beta-glucan immunomodulator which was thought to reduce the risk of staphylococcal wound infection. It made it to phase-III clinical trials to prevent serious postoperative infection in GI surgical patients—e.g., for Crohn’s disease or ulcerative colitis.
References in periodicals archive ?
Last week the Company announced the discontinuation of its Phase III clinical trial of Betafectin PGG-glucan for the prevention of serious infections in upper gastrointestinal (GI) surgery patients.
Alpha Beta Technology is a biotechnology company that manufactures Betafectin, an immunostimulant drug used to reduce infection rates in surgical patients.
0 mg/kg Betafectin in patients undergoing upper (non-colorectal) GI surgeries who are at risk of post-operative infections.
We are pleased about the significant progress we have made on Betafectin and our anti-fungal programs," said Spiros Jamas, Sc.
Betafectin is a novel anti-infective immunomodulator being developed by Alpha-Beta Technology (Nasdaq: ABTI) (ABTI) for preventing infections in surgery patients whose immune system has been weakened by disease and are at high risk for post-surgical infections.
Betafectin is a novel anti-infective immunomodulator being developed by Alpha-Beta Technology (ABTI) for preventing infections in surgery patients whose immune system has been weakened by disease and are at high risk for post-surgical infections.
Over the past several months, we have remained focused on moving forward with the confirmatory Phase III study of Betafectin in upper gastrointestinal surgery patients and, more recently, with the Phase II trial of Betafectin in inflammatory bowel disease patients," said Spiros Jamas, President and CEO of Alpha-Beta Technology.
Certain factors that might cause such differences include, but are not limited to, the following: further analysis of the data from the Company's Phase III clinical trial; the results of the additional Betafectin clinical trial and the outcome of that trial; the outcome of its other clinical development programs; obtaining the requisite regulatory approvals for Alpha-Beta Technology's products from the U.
The regulatory path for Betafectin follows a meeting with the FDA to review the prior study results and the Company's plans for advancing the product's development.
In addition to Betafectin PGG-glucan, a proprietary carbohydrate immunotherapeutic for infectious disease indications, the Company has an anti-infective research program to discover immunomodulatory agents as well as direct inhibitors of fungal and cell wall synthesis.
This reduction is essential to ensuring that we have the resources to see Betafectin through to commercialization," said Spiros Jamas, Sc.
We have recently announced the preliminary analysis of the results of our Phase III clinical trial of Betafectin for the prevention of post-operative infection and are focusing our efforts on completing the analysis," said Spiros Jamas, Sc.