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Betablocker

   Also found in: Dictionary/thesaurus, Wikipedia 0.15 sec.
Betablocker (beta-adrenergic blocker)
A class of drugs that bind beta-adrenergic receptors and thereby decrease the ability of the body's own natural epinephrine to bind to those receptors, leading to inhibition of various processes in the body's sympathetic system. Betablockers can slow the heart rate, constrict airways in the lungs, lower blood pressure, and reduce aqueous secretion by ciliary tissues in the eye.
Mentioned in: Glaucoma


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To investigate the significance of these genetic differences, Stefan Engelhardt and his colleagues at the University of Wurzburg, Germany, tested three betablockers, including carvedilol, on heart cells from rats that had either the arg389 or gly389 variant.
Twenty-three of the subjects had had coronary bypass surgery or percutaneous transluminal coronary angioplasty, 27 had history of myocardial infarction, and 31 used betablockers.
Although cost data were not included in tiffs analysis, many of the practices such as the appropriate use of prophylaxis to prevent venous thromboembolism in patients at risk and the use of perioperative betablockers in appropriate patients to prevent perioperative morbidity and mortality are relatively inexpensive and would be expected to provide a strong return on investment.
 
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